This episode I focus on the hormones testosterone and estrogen and the way they influence the mind, physique, and conduct at ages after puberty. I additionally focus on how varied behaviors comparable to train (resistance and endurance coaching) and intercourse, or observing intercourse influence these hormones and their ranges. I ask: “what specifically is it about such activities that impact testosterone and estrogen?”; the resounding theme is that when our nervous system is activated particularly methods it drives our endocrine system and vascular system to activate or repress sure hormone networks in predictable methods. I additionally focus on peer-reviewed research and protocols addressing (at a mechanistic stage) how mild, chilly and warmth, and respiration (respiratory) can positively or negatively influence testosterone and estrogen. And we focus on particular dietary supplements and compounds that peer-reviewed research illustrate can alter testosterone and estrogen ranges: by altering their binding to different proteins, by elevating them immediately, or by altering different hormones launched from the mind and pituitary. I focus on optimization within the regular reference ranges for these hormones, and I focus on pheromones, apnea, menstrual cycles, menopause and andropause. As at all times a mixture of fundamental science, organic mechanisms and instruments and protocols are mentioned.
**Note: Future episodes will give attention to the science of prescription hormone substitute therapies, the science of hormone-based contraception and the position of testosterone, estrogen and different compounds in fertility, athletic efficiency and restoration.
#HubermanLab #Testosterone #Estrogen
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References:
Examine: https://examine.com
“Behavioral Endocrinology” by Nelson and Kriegsfeld fifth Ed.
Timestamps
00:00:00 Introduction
00:05:50 Hormone Optimization
00:07:00 Salutogenesis: A Powerful Way to Conceptualize Health
00:10:03 Estrogen and Testosterone: Sources, Levels & Ratios
00:15:46 The Power of Competition, Plus: Anxiety, Persistence & Dopamine
00:20:58 Testosterone & Libido Pre-Ovulation
00:21:48 Estrogen & Sexual Receptivity; Libido In Males
00:23:10 How Sex Behavior Impacts Testosterone: Observing vs. Actual vs. Abstinence
00:26:46 Testosterone & Prolactin: Sex Seeking vs Pair Bonding
00:27:30 DHEA (dehydroepiandrosterone): Effects on Levels/Ratios
00:28:45 Behaviors That Decrease Testosterone (& Cortisol): Parenting & Prolactin
00:31:24 How Illness Impacts Testosterone & Estrogen: Cytokines, e.g., IL-6
00:33:20 How Exactly Do Behaviors Change Hormones?
00:34:18 Pheromones: Miscarriage, Menstrual Cycles, Puberty Onset, & Mate Recognition
00:43:33 Apnea: A Powerful Bi-Directional Influence On Estrogen & Testosterone
00:47:44 Mouth vs. Nose Breathing & Hormone Levels: Effects Via Sleep and Direct Effects
00:51:11 How Sleep Adjusts Cortisol/Testosterone and Cortisol/Estrogen Ratios
00:53:49 02:CO2 Ratios, Nasal Breathing During Exercise
00:56:30 Light Viewing Patterns & Hormones: Dopamine, GnRH
00:57:44 Spring Fever: Tyrosinase, Hair Color, Mating Frequency
01:04:39 Specificity of Hormone Effects
01:06:03 Temperature: Cold & Hot Gonads
01:14:10 How To Exercise: Types, Effort Level, Sequencing
01:21:42 Cardio/Endurance vs. Resistance Training (First or Last?) Yes, It Matters
01:24:41 Estrogen & Menopause: Compounds That May Ameliorate/Reverse Symptoms
01:33:18 Nutrients That Optimize The Foundation For Hormones
01:36:00 Opioids as Severe Hormone Disruptors
01:37:23 Testes, Antlers & Ovaries
01:38:50 Creatine & Increasing DHT (Dihydrotestosterone)
01:40:14 Free and Bound Testosterone: SHBG (Sex Hormone Binding Globulin), Tongat Ali
01:43:23 Nettles, Prostate, Boron, & Blood Brain Barrier
01:45:27 Hormone Related Cancers: Sometimes Reducing Estrogen and Testosterone Is Optimal
01:47:43 Ecdysteroids: Mimic Mammalian Hormones
01:51:50 Optimizing Brain Hormones: Chorionic Gonadatropin, Fadogia Agrestis
01:57:18 Additional Compounds, Liver Toxicity, Overall Milieu
01:59:17 Summary: And Note About Additional Related Topic Coverage Coming
Disclaimer: https://hubermanlab.com/disclaimer/
Title Card Photo Credit: Mike Blabac https://www.blabacphoto.com
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